Hydrochloric Acid → HCID 12232366, compound

Participants

Reaction Steps

21.2 g of 2-fluoro-10,11-dihydro-dibenzo[b,f]thiepin-10-ol, 110 ml of benzene and 7.9 g of finely powdered calcium chloride are saturated with hydrochloric acid gas at 15° C (2 hours). The precipitate is filtered off and washed with benzene. The filtrate is evaporated under reduced pressure. There is obtained 10-chloro-2-fluoro-10,11-dihydro-dibenzo-[b,f]thiepin as pink crystals which melt at 90°-92° C.

Provenance & Evidence