反应详情

温度

40 °C

14 g of 10,11-dihydro-2-dimethylsulphamoyl-dibenzo[b,f]-thiepin-10-one in 200 ml of dioxane are treated with 3.5 g of sodium borohydride in 15 ml of water and the mixture is stirred at 40° C for 4 hours. The mixture is evaporated under reduced pressure and the residue taken up in ethyl acetate and water. The organic phase is washed with water, dried and evaporated. 10,11-dihydro-2-dimethylsulphamoyl-dibenzo[b,f]-thiepin-10-ol is obtained.

1. customThe mixture is evaporated under reduced pressure
2. washThe organic phase is washed with water
3. customdried
4. customevaporated