HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Piperazinecarboxylic acid, ethyl ester → HCID 21456042, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| Reactant | HCID 12539110 | HCID 12539110 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 21456042 | HCID 21456042 | — |
Reaction Steps
19.7 g of 10-chloro-10,11-dihydro-2-methyl-dibenzo-[b,f]thiepine dissolved in 100 ml of chloroform are heated under reflux for 24 hours together with 36.5 g of 1-carbethoxy-piperazine. Then the mixture is concentrated under reduced pressure and the residue crystallised from acetone/hexane. There is obtained 1-carbethoxy-4-(10,11-dihydro-2-methyl-dibenzo[b,f]thiepin-10-yl)-piperazine of melting point 96°-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04006144 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-329d8f0fb5e746959c77460f0db4ad39 |
| Source note | uspto-grants-1977_02 |