Thionyl Chloride → Methyl 2-[4-[[(5-chloro-4-ethyl-1H-imidazol-2-yl)carbonyl]amino]phenyl]-4-oxazolecarboxylate

Participants

Reaction Steps

The same operation as in Example (91c) was performed using 4-chloro-5-ethyl-1H-imidazole-2-carboxylic acid (0.13 g, 0.75 mmol), thionyl chloride (5 mL), methyl 2-(4-aminophenyl)-1,3-oxazole-4-carboxylate obtained in Example (96b) (0.15 g, 0.69 mmol) and pyridine (5 mL), to obtain 0.12 g of the title compound as a light purple solid (47%).

Provenance & Evidence