Acetic Anhydride → HCID 178467435, compound

HRID 435731Notes

Reaction equation

HRID 435731 reaction equation
[NH:1]1[CH:5]=[N:4][C:3]([C:6]([NH2:8])=[O:7])=[N:2]1.[C:9](OC(=O)C)(=[O:11])[CH3:10]>>[C:9]([C:5]1[NH:1][N:2]=[C:3]([C:6]([NH2:8])=[O:7])[N:4]=1)(=[O:11])[CH3:10]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 178513825HCID 178513825, compound

Product 1

HCID 178467435HCID 178467435, compound

Procedure

A mixture of 0.2 g. of 1,2,4-triazole-3-carboxamide and 0.5 ml. of acetic anhydride is heated on an oil bath at a temperature of 150° C. for 20 minutes. The wet solid mass is triturated with diethyl ether and collected and washed with diethyl ether yielding 0.2 g. of colorless solid. This solid is recrystallized from acetonitrile giving a colorless solid, m.p. 212°-215° C. (dec).

Workup

  1. additionA mixture of 0.2 g
  2. customThe wet solid mass is triturated with diethyl ether
  3. customcollected
  4. washwashed with diethyl ether yielding 0.2 g
  5. customThis solid is recrystallized from acetonitrile giving a colorless solid, m.p. 212°-215° C. (dec)

Sources & evidence

ORD record
ord-7733fd560024412992bc2c486c117757
Source dataset
uspto-grants-1977_02
Patent number
US04006159

Reaction notes

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