Acetic Anhydride → HCID 70603769, compound

HRID 435752Notes

Reaction equation

HRID 435752 reaction equation
[OH:1][CH:2]([CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH:3]=[CH:4][C@@H:5]1[CH2:9][CH2:8][C:7](=[O:10])[C@H:6]1[CH2:11]/[CH:12]=[CH:13]\[CH2:14][CH2:15][CH2:16][C:17]([O:19][CH3:20])=[O:18].[C:26](OC(=O)C)(=[O:28])[CH3:27]>N1C=CC=CC=1>[C:26]([O:1][CH:2]([CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH:3]=[CH:4][C@@H:5]1[CH2:9][CH2:8][C:7](=[O:10])[C@H:6]1[CH2:11]/[CH:12]=[CH:13]\[CH2:14][CH2:15][CH2:16][C:17]([O:19][CH3:20])=[O:18])(=[O:28])[CH3:27]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 70603754HCID 70603754, compound

Product 1

HCID 70603769HCID 70603769, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A solution of the compound of formula I, methyl trans,cis- 7-[2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoate (5 g), described in Example 161, in 50 ml of pyridine and 50 ml of acetic anhydride is stirred at room temperature for 4 hr. The solution is diluted with ice-water and extracted with ether. The ether is washed with 10% H2SO4, water 10% Na2CO3 and water, dried (Na2SO4) and evaporated to give the title compound.

Workup

  1. extractionextracted with ether
  2. washThe ether is washed with 10% H2SO4, water 10% Na2CO3 and water
  3. dry with materialdried (Na2SO4)
  4. customevaporated

Sources & evidence

ORD record
ord-9efa22789c4e4b929e1f1116219ba6e8
Source dataset
uspto-grants-1977_02
Patent number
US04006136

Reaction notes

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