HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (1,3-Dihydroxy-2-ethyl-4,5-dimethyl-6-indanyloxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium borohydride | HCID 4192641 | — |
| Reactant | HCID 21481314 | HCID 21481314 | — |
| Solvent | Water | HCID 962 | — |
| Product | (1,3-Dihydroxy-2-ethyl-4,5-dimethyl-6-indanyloxy)acetic acid | HCID 21481322 | — |
Reaction Conditions
| Temperature | 5 °C |
|---|
Reaction Steps
A stirred suspension of (1,3-dioxo-2-ethyl-4,5-dimethyl-6-indanyloxy)acetic acid (5.52 g., 0.02 mole) in water (200 ml.) is cooled to 5° C. and treated with a solution of potassium borohydride (4.0 g., 0.075 mole) in water (200 ml.) during a 1 hour period. The reaction is stirred for one hour then acidified with hydrochloric acid affording (1,3-dihydroxy-2-ethyl-4,5-dimethyl-6-indanyloxy)acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04006180 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-f5e0e546cf0b4426b8c643d9b98cf71c |
| Source note | uspto-grants-1977_02 |