HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thieno(2,3-c)pyridine → 6-[(4-Amino-2-ethyl-5-pyrimidinyl)methyl]-7-methylthieno[2,3-c]pyridinium chloride hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thieno(2,3-c)pyridine | HCID 9224 | — |
| Reactant | 5-(Bromomethyl)-2-methylpyrimidin-4-amine--hydrogen bromide (1/1) | HCID 12513493 | — |
| Reactant | 5-(Bromomethyl)-2-ethyl-4-pyrimidinamine Hydrobromide | HCID 21416665 | — |
| Reactant | 5-Methylthieno[2,3-c]pyridine | HCID 21416670 | — |
| Reactant | 6-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-thieno[2,3-c]pyridinium chloride hydrochloride | HCID 21416680 | — |
| Reactant | 6-[(4-Amino-2-ethyl-5-pyrimidinyl)methyl]-5-methylthieno[2,3-c]pyridinium chloride hydrochloride | HCID 21416685 | — |
| Product | 6-[(4-Amino-2-ethyl-5-pyrimidinyl)methyl]-7-methylthieno[2,3-c]pyridinium chloride hydrochloride | HCID 21416667 | — |
Reaction Steps
The compounds, 6-[(4-amino-2-ethyl-5-pyrimidinyl)-methyl]-5-methylthieno[2,3-c]pyridinium chloride hydrochloride and 6-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-thieno[2,3-c]pyridinium chloride hydrochloride can be prepared following the above reaction, using the reactants 4-amino-2-ethyl-5-pyrimidinyl-methyl bromide hydrobromide with 5-methylthieno[2,3-c]pyridine or 4-amino-2-methyl-5-pyrimidinyl-methyl bromide hydrobromide with thieno[2,3-c]-pyridine, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04006143 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-afbddd4215f4466d812b853fb0bd67ef |
| Source note | uspto-grants-1977_02 |