Disodium 1,5-naphthalenedisulfonate → HCID 178462823, compound

HRID 435777Notes

Reaction equation

HRID 435777 reaction equation
Cl.[Cl-].[NH2:3][C:4]1[C:9]([CH2:10][N+:11]2[C:12]([CH3:20])=[C:13]3[S:19][CH:18]=[CH:17][C:14]3=[CH:15][CH:16]=2)=[CH:8][N:7]=[C:6](CC)[N:5]=1.[Na+].[Na+].[C:25]1([S:39]([O-:42])(=[O:41])=[O:40])[C:34]2[CH:33]=[CH:32][CH:31]=[C:30]([S:35]([O-:38])(=[O:37])=[O:36])[C:29]=2[CH:28]=[CH:27][CH:26]=1>O>[OH2:36].[C:25]1([S:39]([O-:42])(=[O:41])=[O:40])[C:34]2[CH:33]=[CH:32][CH:31]=[C:30]([S:35]([O-:38])(=[O:37])=[O:36])[C:29]=2[CH:28]=[CH:27][CH:26]=1.[NH2:3][C:4]1[N:5]([CH2:25][CH3:26])[CH2:6][N:7]=[CH:8][C:9]=1[CH2:10][N+:11]1[C:12]([CH3:20])=[C:13]2[S:19][CH:18]=[CH:17][C:14]2=[CH:15][CH:16]=1.[NH2:3][C:4]1[N:5]([CH2:25][CH3:26])[CH2:6][N:7]=[CH:8][C:9]=1[CH2:10][N+:11]1[C:12]([CH3:20])=[C:13]2[S:19][CH:18]=[CH:17][C:14]2=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 74248Disodium 1,5-naphthalenedisulfonateHCID 214166676-[(4-Amino-2-ethyl-5-pyrimidinyl)methyl]-7-methylthieno[2,3-c]pyridinium chloride hydrochloride

Product 1

HCID 178462823HCID 178462823, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a mixture of 6-[(4-amino-2-ethyl-5-pyrimidinyl)methyl]-7-methylthieno[2,3-c]pyridinium chloride hydrochloride (7.14 g., 0.02 mole) and 1,5-naphthalenedisulfonic acid disodium salt (7.73 g., 0.021 mole), there is added 75 ml. water. The reaction mixture is heated on a steam bath for two hours and then cooled to room temperature. The precipitate is collected by filtration, washed with some fresh water, then acetone, and finally air dried to give the product as a colorless, analytically pure solid, 11.25 g. (95%).

Workup

  1. additionis added 75 ml
  2. temperatureThe reaction mixture is heated on a steam bath for two hours
  3. filtrationThe precipitate is collected by filtration
  4. washwashed with some fresh water
  5. dry with materialacetone, and finally air dried
  6. customto give the product as a colorless, analytically pure solid, 11.25 g

Sources & evidence

ORD record
ord-5ea3920c88bf44d09c716e6f2e24931f
Source dataset
uspto-grants-1977_02
Patent number
US04006143

Reaction notes

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