反应详情

A mixture of 19.6 g. (0.1 mole) 4-methyl benzophenone 17.8 g. (0.1 mole) N-bromosuccinimide, 0.4 g. (0.0016 mole) benzoyl peroxide and 200 ml. carbon tetrachloride is refluxed for 18 hours. The mixture is then cooled and filtered, and the resulting solid is suspended in water, filtered and washed with water. The wet solid is dissolved in methylene chloride, washed with water and brine, dried over anhydrous magnesium sulfate and evaporated to give α-bromo-4-benzoyl toluene, m.p. 104° to 109° C.

1. additionA mixture of 19.6 g
2. temperatureThe mixture is then cooled
3. filtrationfiltered
4. filtrationfiltered
5. washwashed with water
6. dissolutionThe wet solid is dissolved in methylene chloride
7. washwashed with water and brine
8. dry with materialdried over anhydrous magnesium sulfate
9. customevaporated