Hydrazine → HCID 21454618, compound

HRID 435910Notes

Reaction equation

HRID 435910 reaction equation
[CH2:1]([NH:7][NH2:8])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH3:9][S:10]([C:12]1[S:16][C:15]([N:17]=[C:18]=[O:19])=[N:14][N:13]=1)=[O:11].NN>C(Cl)Cl>[CH2:1]([N:7]([C:18]([NH:17][C:15]1[S:16][C:12]([S:10]([CH3:9])=[O:11])=[N:13][N:14]=1)=[O:19])[NH2:8])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

5

Reactant 3

HCID 9321HydrazineHCID 38302Hydrazine, hexyl-HCID 540842185-Methylsulfinyl-1,3,4-thiadiazol-2-yl isocyanate

Product 1

HCID 21454618HCID 21454618, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of n-hexylhydrazine (0.3 mole) in methylene chloride (150 ml) is charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. 5-Methylsulfinyl-1,3,4-thiadiazol-2-yl isocyanate dimer (0.1 mole) is then added, with stirring, at room temperature. After the addition is completed the reaction mixture is heated at reflux for a period of about 4 hours. After this time the reaction mixture is stripped of solvent and excess hydrazine to yield the desired product 2-n-hexyl-4-(5-methylsulfinyl-1,3,4-thiadiazol-2-yl)semicarbazide as the residue.

Workup

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. additionAfter the addition
  4. temperatureis heated
  5. temperatureat reflux for a period of about 4 hours

Sources & evidence

ORD record
ord-cec8d714953643fa84933ea56e68563f
Source dataset
uspto-grants-1977_02
Patent number
US04007031

Reaction notes

Loading…