Methyl 2-(3-methoxy-4-nitrophenyl)-1,3-oxazole-4-carboxylate → Methyl 2-(4-amino-3-methoxyphenyl)-1,3-oxazole-4-carboxylate

Participants

Reaction Steps

The same operation as in Example (95b) was performed using methyl 2-(3-methoxy-4-nitrophenyl)-1,3-oxazole-4-carboxylate obtained in Example (102c) (1.46 g, 5.25 mmol), 10% Pd/C (0.3 g) and ethanol (20 mL). The resulting solid was washed with dichloromethane/hexane to obtain 0.88 g of the title compound as a colorless solid (67%).

Provenance & Evidence