Hydrochloric Acid → HCID 12627897, compound

Participants

Reaction Steps

A mixture of 10.5g. of 2-(2ethyl-1-oxoindan-6-yl)propionic acid, 20g. of zinc amalgam, 30 ml. of conc. hydrochloric acid, 150 ml. of dioxane and 20 ml. of water was heated under reflux for 15 hours. After completion of the reaction, the reaction mixture was extracted with ether and the ether extract was washed with water and dried over anhydrous sodium sulfate. The solvent was distilled off from the extract and the residue was subjected to vacuum distillation to give 8.2g. of the desired product as a colorless oily substance of b.p. 165° - 166° C./1.5 mmHg.

Provenance & Evidence