反应详情

Into a quarter-litre flask equipped with a condenser were introduced 27.2 g (0.128 mol) of 2-ethyl-3-carboxy-benzo[b]thiophene and 100 ml of thionyl chloride. The solution was refluxed for 3 hours and the excess of thionyl chloride was then eliminated by distillation. The residue was distilled and 27.1 g of 2-ethyl-3-chlorocarbonyl-benzo[b]thiophene were obtained representing a yield of 91%; b.p. 110/120° C (0.05 mm/Hg).

1. customInto a quarter-litre flask equipped with a condenser
2. temperatureThe solution was refluxed for 3 hours
3. distillationthe excess of thionyl chloride was then eliminated by distillation
4. distillationThe residue was distilled