Ethyl cis(+/-)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-1,3-oxazole-4-carboxylate → Ethyl cis(+/-)-2-(4-amino-3-methoxypiperidin-1-yl)-1,3-oxazole-4-carboxylate

Participants

Reaction Steps

The same operation as in Example (95b) was performed using ethyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-1,3-oxazole-4-carboxylate obtained in Example (103c) (0.7 g, 1.74 mmol), 10% Pd/C (0.25 g) and ethanol (10 mL), to obtain 0.48 g of the title compound as a yellow amorphous solid (100%).

Provenance & Evidence