Acetamide → N-methyl-[N'-(2,6-dimethylphenyl)-N'-chloroacetyl-amino]-acetamide

HRID 436234Notes

Reaction equation

HRID 436234 reaction equation
[CH3:1][NH:2][C:3](=[O:19])[CH2:4][N:5]([C:10]1[C:15]([CH2:16]C)=[CH:14][CH:13]=[CH:12][C:11]=1[CH3:18])[C:6](=[O:9])[CH2:7][Cl:8].CN(C)C(=O)CN(C1C(C)=CC=CC=1C)C(=O)CCl.CN(C)C(=O)CN(C1C(CC)=CC=CC=1C)C(=O)CCl.C(NC(=O)CN(C1C(C)=CC=CC=1C)C(=O)CCl)C.C(N)(=O)C.CN(C)C(=O)CN(C1C(C)=CC=CC=1Cl)C(=O)CCl.CNC(=O)CN(C1C(C)=CC=CC=1Cl)C(=O)CCl.CNC(=O)CN(C1C(CC)=CC=CC=1CC)C(=O)CCl>>[CH3:1][NH:2][C:3](=[O:19])[CH2:4][N:5]([C:10]1[C:15]([CH3:16])=[CH:14][CH:13]=[CH:12][C:11]=1[CH3:18])[C:6](=[O:9])[CH2:7][Cl:8]

Participants

9

Reactant 8

HCID 178AcetamideHCID 19758562N~2~-(Chloroacetyl)-N~2~-(2,6-dimethylphenyl)-N,N-dimethylglycinamideHCID 86734487N-methyl-[N'-(2-methyl-6-ethylphenyl)-N'-chloroacetyl-amino]-acetamideHCID 86734488N,N-dimethyl-[N'-(2-methyl-6-ethylphenyl)-N'-chloroacetylamino]-acetamideHCID 86734489N-ethyl-[N'-(2,6-dimethylphenyl)-N'-chloroacetylamino]-acetamideHCID 86734490N,N-dimethyl-[N'-(2-chloro-6-methylphenyl)-N'-chloroacetyl-amino]-acetamideHCID 86734491N-methyl-[N'-(2-chloro-6-methylphenyl)-N'-chloroacetylamino]-acetamideHCID 86734492N-methyl[N'-(2,6-diethylphenyl)-N'-chloroacetylamino]-acetamide

Product 1

HCID 86734486N-methyl-[N'-(2,6-dimethylphenyl)-N'-chloroacetyl-amino]-acetamide

Procedure

N-methyl-[N'-(2-methyl-6-ethylphenyl)-N'-chloroacetyl-amino]-acetamide; N,N-dimethyl-[N'-(2,6-dimethylphenyl)-N'-chloroacetylamino]-acetamide; N,N-dimethyl-[N'-(2-methyl-6-ethylphenyl)-N'-chloroacetylamino]-acetamide; N-ethyl-[N'-(2,6-dimethylphenyl)-N'-chloroacetylamino]-acetamide; N-ethyl-N'-(2-methyl-6-ethylphenyl)-N'-chloroacetylamino]-acetamide; N,N-dimethyl-[N'-(2-chloro-6-methylphenyl)-N'-chloroacetyl-amino]-acetamide; N-methyl-[N'-(2-chloro-6-methylphenyl)-N'-chloroacetylamino]-acetamide; N-methyl[N'-(2,6-diethylphenyl)-N'-chloroacetylamino]-acetamide.

Sources & evidence

ORD record
ord-d847308931b04b39a092da29209e1c9e
Source dataset
uspto-grants-1977_02
Patent number
US04008066

Reaction notes

Loading…