Benzene → HCID 86734498, compound

Participants

Reaction Steps

Oleic acid (1.8 g.) is dissolved in about 100 ml. of dry benzene and 2.4 g. of oxalyl chloride is added with stirring, under nitrogen, at room temperature. After 2 hours, solvent is removed under reduced pressure in 30° water bath. Fresh dry benzene (100 ml.) is added and 9.4 g. of cyclopropylmethyl alcohol. The reaction mixture is stirred overnight at room temperature. The reaction is worked up by washing with water and brine, drying over calcium sulfate and evaporation of solvent to yield the cyclopropylmethyl ester of oleic acid (cyclopropylmethyloctadec-9-enoate) b.p. 120° (bath) at 0.01 mm., which can be further purified by distillation.

Provenance & Evidence