HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassio isocyanate → 4-nitro-2-methyl-N-(beta-ureido-ethyl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassio isocyanate | HCID 11051572 | — |
| Reactant | N-(2-methyl-4-nitrophenyl)ethane-1,2-diamine hydrochloride | HCID 17336835 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-nitro-2-methyl-N-(beta-ureido-ethyl)aniline | HCID 21454196 | 80.6% |
Reaction Steps
24.3 g (0.3 mole) of potassium isocyanate in solution in 75 cm3 of water is added to 57.9g (0.25 mole) of 4-nitro-2-methyl-N-(β-aminoethyl) aniline monohydrochloride in 235 cm3 of water at 60°. After keeping the reaction mixture for 15 minutes in a boiling water bath, drying yields 48 g of 4-nitro-2-methyl-N-(β-ureido-ethyl)aniline which, after recrystallization in acetic acid, melts at 186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04008272 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-72984c75cfb44b0d8dba5c30d58b4764 |
| Source note | uspto-grants-1977_02 |