HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N-(2-chloro-4-nitrophenyl)ethane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 1,2-Dichloro-4-nitrobenzene | HCID 7443 | — |
| Product | N-(2-chloro-4-nitrophenyl)ethane-1,2-diamine | HCID 2829584 | — |
Reaction Steps
Ethylene diamine is reacted with 3,4-dichloronitrobenzene to form 4-nitro-2-chloro-N-(β-aminoethyl) aniline, which is reacted in an acetic solution with potassium isocyanate to form 4-nitro-2-chloro-N-(β-ureidoethyl) aniline. This latter compound is reduced with hydrazine in the presence of Raney's nickel, yielding 4-amino-2-chloro-N-(β-ureidoethyl) aniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04008272 |
| Source dataset | uspto-grants-1977_02 |
| ORD ID | ord-83b9628b4da54dcbb44379db08fb5aa8 |
| Source note | uspto-grants-1977_02 |