Sodium Carbonate → HCID 22613473, compound

HRID 436357Notes

Reaction equation

HRID 436357 reaction equation
Cl.[C:2]([NH:6][NH2:7])([CH3:5])([CH3:4])[CH3:3].C(=O)([O-])[O-].[Na+].[Na+].[C:14](Cl)(=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16]>O>[C:14]([NH:7][NH:6][C:2]([CH3:5])([CH3:4])[CH3:3])(=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16]

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 62493Pivaloyl chlorideHCID 81889tert-Butylhydrazine monohydrochloride

Product 1

HCID 22613473HCID 22613473, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
10 °C

Procedure

A solution of 40.8 g. (0.33 m.) of tert.-butylhydrazine hydrochloride in 300 ml. of distilled water was placed in a 500 ml. 4 neck, round bottom flask equipped with a high speed mechanical stirrer, a thermometer and a condenser, and cooled to 10° C. The solution was made basic by adding 24.3 g. (0.225 m.) of sodium carbonate and then 18.9 g. (0.15 m.) of pivaloyl chloride was added dropwise over 1 hour holding the temperature below 10° C. with an ice bath. The mixture was stirred for 3 hours and the white solid which formed was filtered off and dried. The product weight 16.5 g. after drying and had a melting range of 97°-105° C.

Workup

  1. custom4 neck, round bottom flask equipped with a high speed mechanical stirrer
  2. additionby adding 24.3 g
  3. customthe temperature below 10° C.
  4. customthe white solid which formed
  5. filtrationwas filtered off
  6. customdried
  7. customafter drying

Sources & evidence

ORD record
ord-50705943176040b9a332d893e6a4baa9
Source dataset
uspto-grants-1977_02
Patent number
US04008273

Reaction notes

Loading…