Acetic Acid → 1-Methyl-s-triazolo[4,3-a]quinoxaline

HRID 436368Notes

Reaction equation

HRID 436368 reaction equation
[NH:1]([C:3]1[CH:12]=[N:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1)[NH2:2].[C:13](O)(=O)[CH3:14]>>[CH3:13][C:14]1[N:4]2[C:5]3[C:10]([N:11]=[CH:12][C:3]2=[N:1][N:2]=1)=[CH:9][CH:8]=[CH:7][CH:6]=3

Participants

3

Reactant 2

HCID 176Acetic AcidHCID 2898472-Hydrazinoquinoxaline

Product 1

HCID 218174041-Methyl-s-triazolo[4,3-a]quinoxaline

Procedure

A 5 g. portion of 2-hydrazinoquinoxaline was stirred at reflux temperature in acetic acid for 3 hours. The reaction mixture was then cooled, and was evaporated to dryness under vacuum. The product was found to melt at 210°-12° C. without purification, and was identified as 1-methyl-s-triazolo[ 4,3-a]quinoxaline by NMR analysis and elemental microanalysis, the results of which follow.

Workup

  1. temperatureThe reaction mixture was then cooled
  2. customwas evaporated to dryness under vacuum
  3. customto melt at 210°-12° C. without purification
  4. customthe results of which

Sources & evidence

ORD record
ord-4a363311389b443a82fd6b09271767e6
Source dataset
uspto-grants-1977_02
Patent number
US04008322

Reaction notes

Loading…