反应详情

A mixture of 25 g (0.13 m) of diphenylacetonitrile and 27 g (0.13 m) of phosphorus pentachloride is heated at 125° for 4 hours. The reaction mixture is poured into water and extracted with ether. The combined ether extracts are washed with 10% hydrochloric acid, saturated aqueous sodium bicarbonate solution and dried over magnesium sulfate. The solvent is evaporated to give 27 g of crude α-chlorodiphenylacetonitrile.

1. temperatureis heated at 125° for 4 hours
2. extractionextracted with ether
3. washThe combined ether extracts are washed with 10% hydrochloric acid, saturated aqueous sodium bicarbonate solution
4. dry with materialdried over magnesium sulfate
5. customThe solvent is evaporated