Butyl cis(+/-)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-isopropyl-1,3-oxazole-4-carboxylate → Butyl cis(+/-)-2-(4-amino-3-methoxypiperidin-1-yl)-5-isopropyl-1,3-oxazole-4-carboxylate

Participants

Reaction Steps

The same operation as in Example (95b) was performed using butyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-isopropyl-1,3-oxazole-4-carboxylate obtained in Example (111b) (0.45 g, 0.95 mmol), 10% Pd/C (0.2 g) and methanol (3 mL), to obtain 0.31 g of the title compound as a yellow oily substance (96%).

Provenance & Evidence