Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43646Generated: October 29, 2026

Methanol → HCID 86648596, compound

https://huagongshe.com/reaction/43646

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantLithium HydroxideHCID 3939—
ReactantHCID 86648595HCID 86648595—
SolventTetrahydrofuranHCID 8028—
ProductHCID 86648596HCID 8664859690.9%

Reaction Steps

The same operation as in Example (91d) was performed using butyl cis(±)-2-(4-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-isopropyl-1,3-oxazole-4-carboxylate obtained in Example (111d) (0.15 g, 0.30 mmol), 2 N lithium hydroxide (3 mL, 6 mmol), methanol (3 mL) and THF (5 mL), to obtain 0.12 g of the title compound as a colorless solid (90%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536197B2
Source datasetuspto-grants-2013_09
ORD IDord-5136378aebaa40548e700b77367f3880
Source noteuspto-grants-2013_09