Trimethyl orthoformate → HCID 53787163, compound

Participants

Reaction Steps

32.8 g of 8-(5-formyl-2-furyl)-octanoic acid methyl ester, 15.5 g of trimethyl orthoformate, 16 ml of methanol and 0.3 g of ammonium chloride were mixed and refluxed for 4 hours. The solution was concentrated to dryness on a water bath. The residue was then absorbed in ether, washed with water, dried and distilled. Boiling point 136°-138° C at 0.2 mm Hg.

Provenance & Evidence