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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43661Generated: October 29, 2026

Butyl cis(+/-)-2-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)-5-ethyl-1,3-oxazole-4-carboxylate → HCID 86648604, compound

https://huagongshe.com/reaction/43661

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl cis(+/-)-2-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)-5-ethyl-1,3-oxazole-4-carboxylateHCID 86648605—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 86648604HCID 8664860494.3%

Reaction Steps

The same operation as in Example (95b) was performed using butyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)-5-ethyl-1,3-oxazole-4-carboxylate obtained in Example (113g) (1.01 g, 2.1 mmol), 10% Pd/C (0.25 g) and methanol (15 mL), to obtain 0.70 g of the title compound as a light yellow oily substance (95%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536197B2
Source datasetuspto-grants-2013_09
ORD IDord-0b797372902b4072bbb04000a36eb18e
Source noteuspto-grants-2013_09