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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 43665Generated: October 29, 2026

Butyl cis(+/-)-2-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)-5-methyl-1,3-oxazole-4-carboxylate → HCID 86648608, compound

https://huagongshe.com/reaction/43665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantButyl cis(+/-)-2-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)-5-methyl-1,3-oxazole-4-carboxylateHCID 86648609—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 86648608HCID 8664860894%

Reaction Steps

The same operation as in Example (95b) was performed using butyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-propoxypiperidin-1-yl)-5-methyl-1,3-oxazole-4-carboxylate obtained in Example (114a) (0.98 g, 2.1 mmol), 10% Pd/C (0.25 g) and methanol (15 mL), to obtain 0.67 g of the title compound as a light yellow oily substance (95%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536197B2
Source datasetuspto-grants-2013_09
ORD IDord-d4878ec3e95f467e8eb5a7d2f214b585
Source noteuspto-grants-2013_09