反应详情

A mixture of 25 g. of methyl 6-methoxy-2-naphthylacetate, 15 g. of sodium carbonate, 200 ml. of methanol, and 25 ml. of water are stirred for 24 hours. The reaction mixture is then acidified with 200 ml. of 2 N hydrochloric acid and extracted with methylene chloride. The extracts are combined, washed with water, dried over sodium sulfate, and evaporated to yield 6-methoxy-2-naphthylacetic acid.

1. additionA mixture of 25 g
2. extractionof 2 N hydrochloric acid and extracted with methylene chloride
3. washwashed with water
4. dry with materialdried over sodium sulfate
5. customevaporated