Dimethyl Sulfate → HCID 20320251, compound

HRID 436693Notes

Reaction equation

HRID 436693 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]1=[C:10]([C:13]#[N:14])[C:11]#[N:12].[OH-].[Na+].S(OC)(O[CH3:21])(=O)=O>O>[CH3:21][N:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[O:1][C:2]1=[C:10]([C:13]#[N:14])[C:11]#[N:12]

Participants

5

Reactant 3

HCID 6497Dimethyl SulfateHCID 14798Sodium HydroxideHCID 5012293Propanedinitrile, 2(3H)-benzoxazolylidene-

Product 1

HCID 20320251HCID 20320251, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

9.15 g. (0.05 M) of 2-benzoxazolinylidene-malononitrile and 16.0 g. (0.4 M) of sodium hydroxide are dissolved in 500 ml. of water. The solution is brought to 5° C. while stirring and, over a period of 1 hour, 25.2 g. (0.2 M) of dimethyl sulfate are added dropwise. The resulting crystals are filtered off under suction, washed with water and dried to obtain 3-methyl-benzoxazolinylidene-malononitrile of melting point 198°-200° C.

Workup

  1. customis brought to 5° C.
  2. filtrationThe resulting crystals are filtered off under suction
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-1e77e7be6260497dbf0b09d5dfa32625
Source dataset
uspto-grants-1977_06
Patent number
US04028089

Reaction notes

Loading…