2-(Bis(methylsulfanyl)methylidene)propanedinitrile → 2-Benzoxazolinylidene-cyanoacetic acid morpholide

HRID 436696Notes

Reaction equation

HRID 436696 reaction equation
CSC(SC)=[C:4]([C:7]#N)[C:5]#[N:6].CS[C:13](SC)=[C:14]([C:23]#[N:24])[C:15]([N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1)=[O:16]>C(O)C>[O:16]1[C:15]2[CH:14]=[CH:13][CH:7]=[CH:4][C:5]=2[NH:6][C:13]1=[C:14]([C:23]#[N:24])[C:15]([N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1)=[O:16]

Participants

4

Reactant 2

HCID 992292-(Bis(methylsulfanyl)methylidene)propanedinitrileHCID 40508123,3-Bis(methylthio)-2-cyanoacrylic acid morpholide

Product 1

HCID 67957212-Benzoxazolinylidene-cyanoacetic acid morpholide

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The procedure described in Example 1 is repeated using, instead of 3,3-bis(methylthio)-2-cyanoacrylonitrile, an equivalent amount of 3,3-bis(methylthio)-2-cyanoacrylic acid morpholide and holding the mixture under reflux for 24 hours to obtain 2-benzoxazolinylidene-cyanoacetic acid morpholide of melting point 217°-219° C. (from ethanol).

Workup

  1. temperatureunder reflux for 24 hours

Sources & evidence

ORD record
ord-fba76cebadbb411485614ba642f7092d
Source dataset
uspto-grants-1977_06
Patent number
US04028089

Reaction notes

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