HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-1,1,1-trifluoro-2-propanone → HCID 54536245, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-1,1,1-trifluoro-2-propanone | HCID 79008 | — |
| Reactant | 7-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepine | HCID 12390874 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54536245 | HCID 54536245 | — |
Reaction Steps
In the manner given in Example 1, 7-chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine in tetrahydrofuran can be treated with 1,1,1-trifluoro-3-bromopropanone under nitrogen to give 7-chloro-2-[[2-bromo-1-(trifluoromethyl)ethylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04028356 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-34e2c714d23541ad8c63ec2fd513e167 |
| Source note | uspto-grants-1977_06 |