Ethanamine, 2,2,2-trifluoro- → 1-(Methylsulfanyl)-2-nitro-N-(2,2,2-trifluoroethyl)ethen-1-amine

HRID 436853Notes

Reaction equation

HRID 436853 reaction equation
[F:1][C:2]([F:6])([F:5])[CH2:3][NH2:4].[CH3:7][S:8]([C:10](SC)=[CH:11][N+:12]([O-:14])=[O:13])=O>CO>[CH3:7][S:8][C:10]([NH:4][CH2:3][C:2]([F:6])([F:5])[F:1])=[CH:11][N+:12]([O-:14])=[O:13]

Participants

4

Reactant 2

HCID 9773Ethanamine, 2,2,2-trifluoro-HCID 544870941-Nitro2-methylthio-2-methylsulphinylethylene

Product 1

HCID 713918481-(Methylsulfanyl)-2-nitro-N-(2,2,2-trifluoroethyl)ethen-1-amine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A solution of 2,2,2-trifluoroethylamine (4.0 g) in methanol (45 ml) was added dropwise to a suspension of 1-methylsulphinyl-1-methylthio-2-nitroethylene (3.6 g) in methanol (150 ml) at 20° for 24 hours. Evaporation of the reaction mixture and recrystallisation from ether gave the title compound as a pale orange crystalline solid m.p. 101°-102°.

Workup

  1. customEvaporation of the reaction mixture and recrystallisation from ether

Sources & evidence

ORD record
ord-2e127415b22b40d1907b405abbf0e50a
Source dataset
uspto-grants-1977_06
Patent number
US04028379

Reaction notes

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