Hydrochloric Acid → HCID 178513040, compound

Participants

Reaction Steps

161.0 G. of 1-phenethylbiguanide.HCl, 101.0 g. of sodium dichloroacetae and 216.0 g. of dichloroacetic acid were boiled together in 4.5 l. of absolute ethyl acetate at reflux for 1 hour. The hot solution was filtered under suction in order to separate the precipitated sodium chloride. The filtrate was concentrated in vacuo and treated with diisopropylether, whereby 1-phenethylbiguanide bis-(dichloroacetate) crystallized out analytically pure, M.P.: 131°-132° C.

Provenance & Evidence