2-Allylaminoacetaldehyde → HCID 20357128, compound

HRID 436988Notes

Reaction equation

HRID 436988 reaction equation
[Cl:1][C:2]1[CH:13]=[CH:12][C:5]2[N:6]=[C:7]([N:9]=[C:10]=[O:11])[S:8][C:4]=2[CH:3]=1.[CH2:14]([NH:17][CH2:18][CH:19]=[O:20])[CH:15]=[CH2:16]>C1C=CC=CC=1>[CH2:14]([N:17]([CH2:18][CH:19]=[O:20])[C:10]([NH:9][C:7]1[S:8][C:4]2[CH:3]=[C:2]([Cl:1])[CH:13]=[CH:12][C:5]=2[N:6]=1)=[O:11])[CH:15]=[CH2:16]

Participants

4

Reactant 2

HCID 205484762-AllylaminoacetaldehydeHCID 45077457HCID 45077457, compound

Product 1

HCID 20357128HCID 20357128, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

6-Chlorobenzothiazol-2-yl isocyanate dimer (0.1 mole), the dimethyl acetal of 2-allylaminoacetaldehyde (0.2 mole) and benzene (100 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer and thermometer. The reaction mixture is stirred at ambient temperatures for a period of about one hour. After this time the reaction mixture is filtered, and the filtrate is stripped of solvent to yield the desired product the dimethyl acetal of 2-[1-allyl-3-(6-chlorobenzothiazol-2-yl)ureido]acetaldehyde as the residue.

Workup

  1. customequipped with a mechanical stirrer
  2. filtrationAfter this time the reaction mixture is filtered

Sources & evidence

ORD record
ord-a41e98c7e5844ce9ae36104afd549363
Source dataset
uspto-grants-1977_06
Patent number
US04029491

Reaction notes

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