2-(Ethylamino)acetaldehyde → HCID 20357141, compound

HRID 436992Notes

Reaction equation

HRID 436992 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([N:12]=[C:13]=[O:14])[S:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.[CH2:15]([NH:17][CH2:18][CH:19]=[O:20])[CH3:16]>C1C=CC=CC=1>[CH2:15]([N:17]([CH2:18][CH:19]=[O:20])[C:13]([NH:12][C:10]1[S:11][C:7]2[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[C:8]=2[N:9]=1)=[O:14])[CH3:16]

Participants

4

Reactant 2

HCID 205484642-(Ethylamino)acetaldehydeHCID 45077456HCID 45077456, compound

Product 1

HCID 20357141HCID 20357141, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4-Methoxybenzothiazol-2-yl isocyanate dimer (0.1 mole), the dimethyl acetal of 2-ethylaminoacetaldehyde (0.2 mole) and benzene (100 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer and thermometer. The reaction mixture is stirred at ambient temperatures for a period of about one hour. After this time the reaction mixture is filtered, and the filtrate is stripped of solvent to yield the desired product the dimethyl acetal of 2-[1-ethyl-3-(4-methoxybenzothiazol-2-yl)ureido]acetaldehyde as the residue.

Workup

  1. customequipped with a mechanical stirrer
  2. filtrationAfter this time the reaction mixture is filtered

Sources & evidence

ORD record
ord-74a64ed2cb7749cd918fa2ac6e6da984
Source dataset
uspto-grants-1977_06
Patent number
US04029491

Reaction notes

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