(+)-Estrone 3-methyl ether → HCID 70631900, compound

HRID 437021Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:20]2[C@H:9]3[CH2:10][CH2:11][C@@:12]4([CH3:19])[C@H:16]([C@@H:8]3[CH2:7][CH2:6][C:5]=2[CH:4]=1)[CH2:15][CH2:14][C@@H:13]4[O:17][CH3:18].COC1C=CC2[C@H]3CC[C@@]4(C)[C@H]([C@@H]3CCC=2C=1)CCC4=O>>[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:20]2[C:9]3=[CH:10][CH2:11][C@@:12]4([CH3:19])[C@H:16]([C@@H:8]3[CH2:7][CH2:6][C:5]=2[CH:4]=1)[CH2:15][CH2:14][C@@H:13]4[O:17][CH3:18]

Participants

Reactant 2

HCID 92895(+)-Estrone 3-methyl ether

HCID 11278001HCID 11278001, compound

Product 1

HCID 70631900HCID 70631900, compound

Procedure

The procedure described in Example 1 hereinbefore was repeated except that 2.3 grams of 3,17β-dimethoxy-13β-methylgona-1,3,5(10)-triene was substituted for the 3-methoxy-13β-methylgona-1,3,5(10)-trien-17-one in that example.

Sources & evidence

ORD record: ord-20cd5610b19946399c75b8ed1d6b344c
Source dataset: uspto-grants-1977_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04029648

Reaction notes

Loading…