HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → HCID 21429937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-[(3,5,6-Trichloropyrazin-2-yl)amino]ethan-1-ol | HCID 21429936 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 21429937 | HCID 21429937 | 30% |
Reaction Steps
(2-Hydroxyethylamino)-trichloropyrazine (12.1 g, 0.05 mol) and crushed KOH (5 g, 85% assay, 0.075 mol) were contacted in refluxing benzene overnight. The solid phase was filtered out and stirred in water, CH2Cl2, and IPA and refiltered after each wash to give 3 g (30% yield) of an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04029657 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-9d964a81c97a4ef0b7e2b401b0ec3a93 |
| Source note | uspto-grants-1977_06 |