5-(2-Chloroethyl)-1,2,3-trimethoxybenzene → 1-[2-(3,4,5-Trimethoxyphenyl)ethyl]-4-benzamidopiperidine

Participants

Reaction Steps

Prepared in exactly the same way as for the compound of Example 1 except that 3,4,5-trimethoxyphenethyl chloride was used in place of cyclohexylethyl bromide. The title compound was obtained as a monohydrate (1.2 g.), m.p. 193°-4° C. (Found: C, 66.7; H, 7.6; N, 6.9. C20H30N2O4. H2O requires C, 66.4; H, 7.5; N, 6.7%).

Provenance & Evidence