反应详情

1-[2-(p-Aminophenyl)ethyl]-4-benzamidopiperidine (2.3 g.) was refluxed for 2 hours with acetic anhydride (22 ml.) in anhydrous pyridine (100 ml.). The solution was refrigerated for 24 hours and a crystalline product was filtered off, which after washing with ether yielded the title compound, m.p. 270°-275° C. (dec.). Found: C, 72.6; N, 7.55; N, 11.6. C22H27N3O2 requires C, 72.3; H, 7.45; N, 11.5%).

1. filtrationa crystalline product was filtered off
2. washwhich after washing with ether