HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrafluoro-m-phenylenediamine dihydrochloride → 4-Amino-1-[2-(2-naphthyl)ethyl]-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| Reactant | 4-Benzamido-1-[2-(2-naphthyl)ethyl]piperidine | HCID 21430613 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-Amino-1-[2-(2-naphthyl)ethyl]-piperidine | HCID 21430577 | 78.6% |
Reaction Steps
4-Benzamido-1-[2-(2-naphthyl)ethyl]piperidine (1.0 g.) was suspended in 6N HCl (40 ml.) and boiled for 96 hr. The resulting solution was worked up in the manner of Example 72 to give the title compound (0.558 g.) as the dihydrochloride, pale yellow needles, m.p. >300° (decomp.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04029801 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-4c8170c8499b46af9196e837392da24e |
| Source note | uspto-grants-1977_06 |