2-(Methylamino)ethanol → HCID 21427790, compound

HRID 437272Notes

Reaction equation

HRID 437272 reaction equation
[CH3:1][C:2]1[CH2:7][CH2:6][CH:5]([CH:8]([CH3:12])[CH2:9][CH:10]=O)[CH2:4][CH:3]=1.[CH3:13][NH:14][CH2:15][CH2:16][OH:17]>>[CH3:13][N:14]([CH2:15][CH2:16][OH:17])[CH2:10][CH2:9][CH:8]([CH:5]1[CH2:6][CH2:7][C:2]([CH3:1])=[CH:3][CH2:4]1)[CH3:12]

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 1109233-Cyclohexene-1-propanal, beta,4-dimethyl-

Product 1

HCID 21427790HCID 21427790, compound

Procedure

The procedure of Example 1 was followed using 50g (0.3 mole) of 3-(4-methyl-3-cyclohexenyl)butyraldehyde and 25g (0.33 mole) of 2-methylaminoethanol. Obtained following distillation was 27g of pure N-methyl-N-(2-hydroxyethyl)-N-[3 . . . butyl]amine as a clear, colorless liquid; bp 104°-106° (0.1mm); ir (τ max. film) 3.0 (m), 3.5 (s), 6.9 (s), 9.6 (s), 12.5 (m) microns; nmr (δ CDCl3) 5.38 (m, 1H), 3.8 (broad m, 1H) 3.6 (m, 2H), 2.5 (m, 4H), 2.2 (s, 3H), 2.1 to 0.8 (m, 16H) ppm; ms (molecular ion) 225.

Workup

  1. customObtained
  2. distillationdistillation

Sources & evidence

ORD record
ord-c56a5f0c800245858b407ff551669983
Source dataset
uspto-grants-1977_06
Patent number
US04030908

Reaction notes

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