Hydrochloric Acid → 2,3,5,6-Tetramethylbenzene-1,4-dicarbonyl dichloride

Participants

Reaction Steps

To a 500 ml. three-necked flask equipped with stirrer, reflux condenser and nitrogen inlet is added 100 grams tetramethylterephthalic acid and 200 ml. thionyl chloride. The mixture is stirred at reflux of 6 hours during which time the acid dissolves and a mixture of sulfur dioxide and hydrogen chloride is evolved. At the end of this period the excess thionyl chloride is removed by distillation. The crude tetramethylterephthaloyl chloride is recrystallized twice from cyclohexane.

Provenance & Evidence