HCID 12535808, compound → HCID 12535850, compound

HRID 437447Notes

Reaction equation

HRID 437447 reaction equation
[O:1]=[C:2]1[NH:7][C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[O:14][CH2:15][CH:16]2[CH2:18][CH2:17]2)=[N:5][CH:4]=[C:3]1[C:19]([O:21]CC)=[O:20].O=C1NC(C2C=CC=CC=2OCCCC)=NC=C1C(O)=O>>[O:1]=[C:2]1[NH:7][C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[O:14][CH2:15][CH:16]2[CH2:17][CH2:18]2)=[N:5][CH:4]=[C:3]1[C:19]([OH:21])=[O:20]

Participants

3

Reactant 2

HCID 12535808HCID 12535808, compoundHCID 12535846HCID 12535846, compound

Product 1

HCID 12535850HCID 12535850, compound

Procedure

The title compound was prepared from ethyl 1,6-dihydro-6-oxo-2-(2-cyclopropylmethoxyphenyl)pyrimidine-5-carboxylate in a manner similar to that described for the preparation of 1,6-dihydro-6-oxo-2-(2-n-butoxyphenyl)pyrimidine-5-carboxylic acid in Example 23. The product had m.p. 219°-220°.

Sources & evidence

ORD record
ord-e93b6f5fe3094c879c56aaf8c30f2991
Source dataset
uspto-grants-1977_06
Patent number
US04031093

Reaction notes

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