HCID 12535822, compound → HCID 12535866, compound

HRID 437449Notes

Reaction equation

HRID 437449 reaction equation
[O:1]=[C:2]1[NH:7][C:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[CH:11]=[CH:10][C:9]=2[O:16][CH2:17][CH2:18][CH3:19])=[N:5][CH:4]=[C:3]1[C:20]([O:22]CC)=[O:21].O=C1NC(C2C=CC=CC=2OCCCC)=NC=C1C(O)=O>>[O:1]=[C:2]1[NH:7][C:6]([C:8]2[CH:13]=[C:12]([O:14][CH3:15])[CH:11]=[CH:10][C:9]=2[O:16][CH2:17][CH2:18][CH3:19])=[N:5][CH:4]=[C:3]1[C:20]([OH:22])=[O:21]

Participants

3

Reactant 2

HCID 12535822HCID 12535822, compoundHCID 12535846HCID 12535846, compound

Product 1

HCID 12535866HCID 12535866, compound

Procedure

The title compound was prepared from ethyl 1,6-dihydro-6-oxo-2-(5-methoxy-2-n-propoxyphenyl)pyrimidine-5-carboxylate in a manner similar to that described for the preparation of 1,6-dihydro-6-oxo-2-(2-n-butoxyphenyl)pyrimidine-5-carboxylic acid in Example 23. The product had m.p. 185°-187°.

Sources & evidence

ORD record
ord-4cb1030747da4b7d96a6b12f828f8e74
Source dataset
uspto-grants-1977_06
Patent number
US04031093

Reaction notes

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