HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus sulfide (P2S5) → 8-Cyano-3-methyl-5,6,7,8-tetrahydroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus sulfide (P2S5) | HCID 14817 | — |
| Reactant | 3-Methyl-5,6,7,8-tetrahydroquinoline-8-carboxamide | HCID 12278227 | — |
| Product | 8-Cyano-3-methyl-5,6,7,8-tetrahydroquinoline | HCID 12278210 | — |
Reaction Steps
3-Methyl-5,6,7,8-tetrahydroquinoline-8-carboxamide was treated with P2S5 to give 3-methyl-8-cyano-5,6,7,8-tetrahydroquinoline which was treated with H2S as described in Example 8 giving the title compound as colourless needles from benzene m.p. 151° (50% yield) (Found: C, 63.71; H, 6.85; N, 13.38% C11H14N2S requires: C, 64.04; H, 6.84; N, 13.58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04031102 |
| Source dataset | uspto-grants-1977_06 |
| ORD ID | ord-27a5e418f1554292b7c739e38fae0a8a |
| Source note | uspto-grants-1977_06 |