反应详情

1-Formyl-2-(4-aminophenyl)hydrazine (7.5 g, 0.05 mole) and butyl isothiocyanate (5.7 g, 0.05 mole) were mixed in ethanol (120 ml) and the mixture was refluxed for 30 minutes. The resulting solution was chilled in ice and upon scratching the product crystallized out as a white solid. The mixture was filtered and the solid was washed with ether. The product was dried to give a pale tan crystalline powder. Yield 9.8 g (74%), m.p. 129°-131° C.

1. temperaturethe mixture was refluxed for 30 minutes
2. temperatureThe resulting solution was chilled in ice
3. customcrystallized out as a white solid
4. filtrationThe mixture was filtered
5. washthe solid was washed with ether
6. customThe product was dried
7. customto give a pale tan crystalline powder