Acetaldehyde → Diphenyl[1-(morpholinosulfonylamino)ethyl]phosphine oxide

HRID 437534Notes

Reaction equation

HRID 437534 reaction equation
[C:1]1([P:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[O:8]C2C=CC=CC=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:21](=O)[CH3:22].[O:24]1[CH2:29][CH2:28][N:27]([S:30]([NH2:33])(=[O:32])=[O:31])[CH2:26][CH2:25]1>ClC1C=CC=CC=1>[C:15]1([P:7](=[O:8])([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:21]([NH:33][S:30]([N:27]2[CH2:28][CH2:29][O:24][CH2:25][CH2:26]2)(=[O:32])=[O:31])[CH3:22])[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

5

Reactant 3

HCID 177AcetaldehydeHCID 2767394-MorpholinesulfonamideHCID 11543680Phenoxydiphenylphosphine

Product 1

HCID 21423545Diphenyl[1-(morpholinosulfonylamino)ethyl]phosphine oxide

Reagents, catalysts & solvents 1

HCID 7964ChlorobenzeneSolvent

Procedure

When a mixture of equimolar quantities of phenyl diphenylphosphinite, acetaldehyde, and morpholinosulfonylamine in chlorobenzene is treated by the procedure used in the preceding experiment, the product is a white solid, mp 215°-217° C., 31P nmr(DMSO-d6) -30.9 ppm.

Workup

  1. additionis treated by the procedure

Sources & evidence

ORD record
ord-57b98001a73040f1bee94cf3083ce7e3
Source dataset
uspto-grants-1977_06
Patent number
US04031170

Reaction notes

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