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HRID437546

反应详情

EQUATION

反应方程式

HRID 437546 的结构方程式

REACTANTS

反应物

2
结构：Clc1ccc(C(Cl)c2ccccc2)cc1
HCID241584

Benzene, 1-chloro-4-(chlorophenylmethyl)-

C13H10Cl2

结构：COc1ccc(CC2(C)CNCCN2)cc1OC
HCID20363969

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(CC2(C)CN(C(c3ccccc3)c3ccc(Cl)cc3)CCN2)cc1OC
HCID21428573

未命名化合物

收率 80%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCC(C)=O
溶剂HCID6569

Methyl ethyl ketone

C4H8O

PROCEDURE

实验过程

If 3-methyl-3-(3,4-dimethoxybenzyl)-piperazine is reacted with p-chlorophenyl-phenylmethyl chloride in methyl ethyl ketone according to Example 2, 1-(p-chlorophenyl-phenylmethyl)-3-methyl-3-(3,4-dimethoxybenzyl)-piperazine is obtained in 80 percent yield after a 12-hour reaction period. The hydrochloride has a melting point of 235°-237° C. (isopropanol).