1-Benzyl-4-(o-tolyloxy)piperidine → 4-(2-Methylphenoxy)piperidine

HRID 437555Notes

Reaction equation

HRID 437555 reaction equation
C([N:8]1[CH2:13][CH2:12][CH:11]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[CH3:21])[CH2:10][CH2:9]1)C1C=CC=CC=1>C(O)C>[C:16]1([CH3:21])[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[O:14][CH:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1

Participants

3

Reactant 1

HCID 214287021-Benzyl-4-(o-tolyloxy)piperidine

Product 1

HCID 36861704-(2-Methylphenoxy)piperidine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

By following the manipulative procedure described in Example 1(b), a solution of 8.3 g of 1-benzyl-4-(o-tolyloxy)piperidine in 100 ml. of ethanol produces a colorless oil of 4-(o-tolyloxy)piperidine.

Sources & evidence

ORD record
ord-885ea744b77b469885b0be60f2d3d672
Source dataset
uspto-grants-1977_06
Patent number
US04031221

Reaction notes

Loading…