Dimethyl Sulfate → HCID 21429243, compound

Participants

Reaction Steps

Adduct (VII) (34.8 g.) was added to a solution of 32 g. NaOH in 200 ml. water. The solution was stirred and 30.8 g. dimethyl sulfate added dropwise, giving a mild exotherm. Stirring was continued at room temperature for 3 hours. Then, the mixture was filtered, acidified with concentrated HCl, and extracted with chloroform. The organic layer was dried and evaporated to give a viscous brown oil. Distillation gave 6.1 g. of naphthol (VIII) as a thick yellow, viscous liquid, b. 178° C./0.1 mm.

Provenance & Evidence